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ChemMedChem

Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABAA Receptors
Navnath Gavande, Nasiara Karim, Graham A. R. Johnston, Jane R. Hanrahan, Mary Chebib

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
Kai-Hsuan Chang, Oliver N. F. King, Anthony Tumber, Esther C. Y. Woon, Tom D. Heightman, Michael A. McDonough, Christopher J. Schofield, Nathan R. Rose

BZM055, an Iodinated Radiotracer Candidate for PET and SPECT Imaging of Myelin and FTY720 Brain Distribution
Emmanuelle Briard, David Orain, Christian Beerli, Andreas Billich, Markus Streiff, Marc Bigaud, Yves P. Auberson


ChemBiochem

Structure and Function of Histone H3 Lysine 9 Methyltransferases and Demethylases
Kimberly Tirrell

Design, Synthesis and Characterization of a New Anionic Cell-Penetrating Peptide: SAP(E)
Irene Martín, Meritxell Teixidó, Ernest Giralt 


Molecular Informatics

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing
Tudor I. Oprea, Sonny Kim Nielsen, Oleg Ursu, Jeremy J. Yang, Olivier Taboureau, Stephen L. Mathias, Irene Kouskoumvekaki, Larry A. Sklar, Cristian G. Bologa

Discovery of a Potent and Selective Hetero-Bivalent AChE Inhibitor via Bioisosteric Replacement
Orazio Nicolotti, Leonardo Pisani, Marco Catto, Francesco Leonetti, Ilenia Giangreco, Angela Stefanachi, Angelo Carotti


Angewandte Chemie IE

Micromachine-Enabled Capture and Isolation of Cancer Cells in Complex Media
Shankar Balasubramanian, Daniel Kagan, Che-Ming Jack Hu, Susana Campuzano, M. Jesus Lobo-Castañon, Nicole Lim, Dae Y. Kang, Maria Zimmerman, Liangfang Zhang, Joseph Wang

Delivery of Intact Transcription Factor by Using Self-Assembled Supramolecular Nanoparticles
Yang Liu, Hao Wang, Ken-ichiro Kamei, Ming Yan, Kuan-Ju Chen, Qinghua Yuan, Linqi Shi, Yunfeng Lu, Hsian-Rong Tseng


Chemistry – A European Journal

Cytotoxicity of Gold(I) N-Heterocyclic Carbene Complexes Assessed by Using Human Tumor Cell Lines
Jennifer Weaver, Sylvain Gaillard, Caroline Toye, Stephen Macpherson, Steven P. Nolan, Andrew Riches

Drug-Delivery Strategies by Using Template-Synthesized Nanotubes
Jillian L. Perry, Charles R. Martin, Jon D. Stewart


Chemistry – An Asian Journal

Enzyme-Responsive Multifunctional Magnetic Nanoparticles for Tumor Intracellular Drug Delivery and Imaging
Yanmei Yang, Junxin Aw, Kai Chen, Fang Liu, Parasuraman Padmanabhan, Yanglong Hou, Zhen Cheng, Bengang Xing

Blocking Effect on Adsorption-Controlled Electrochemiluminescence of CdSe Nanoparticles for Detection of the Neurotransmitter Serotonin
Hui Jiang, Xuemei Wang

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Chemistry & Biodiversity

On the Mechanism of Eukaryotic Cell Penetration by α- and β-Oligoarginines – Targeting Infected Erythrocytes
Faustin Kamena, Bopanna Monnanda, Danielle Makou, Stefania Capone, Krystyna Patora-Komisarska, Dieter Seebach

Synthesis and Antibacterial Evaluation of a Novel Series of 2-(1,2-Dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles
Alessandro Stella, Kenneth Segers, Steven De Jonghe, Bart Vanderhoydonck, Jef Rozenski, Jozef Anné, Piet Herdewijn


Archiv der Pharmazie – Chemistry in Life Science

Protein Kinase C Activators as Synaptogenic and Memory Therapeutics
Miao-Kun Sun, Daniel L. Alkon

Fatty Acid Binding Receptors and Their Physiological Role in Type 2 Diabetes
Gayathri Swaminath


Medicinal Research Reviews

Circulating MicroRNAs: a novel class of biomarkers to diagnose and monitor human cancers
Ke Zen, Chen-Yu Zhang

Drugs that target dynamic microtubules: A new molecular perspective
Richard A. Stanton, Kim M. Gernert, James H. Nettles, Ritu Aneja


Journal of Pharmaceutical Sciences

Impact of product-related factors on immunogenicity of biotherapeutics
Satish Kumar Singh


Journal of Applied Toxicology

Arsenic: toxicity, oxidative stress and human disease
K. Jomova et al

Nanotechnology and human health: risks and benefits
Anna Giulia Cattaneo et al


Journal of Labelled Compounds

Synthetic approaches to regiospecifically mono- and dilabelled arenes
Thomas J. Gregson, John M. Herbert, Eleanor C. Row

Highlighting the versatility of the tracerlab synthesis modules. Part 1: fully automated production of
[18F] labelled radiopharmaceuticals using a Tracerlab FXFN

Xia Shao, Raphaël Hoareau, Brian G. Hockley, Louis J. M. Tluczek, Bradford D. Henderson, Henry C. Padgett, Peter J. H. Scott

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Biomedical Chromatography

Recent advances in sample preparation techniques for effective bioanalytical methods
Prashant Laxman Kole, Gantala Venkatesh, Jignesh Kotecha, Ravi Sheshala

Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules
Wenkui Li and Francis L. S. Tse


Journal of Peptide Science

COMU: A third generation of uranium-type coupling reagents
Ayman El-Faham, Fernando Albericio

Optimization of oxidative folding methods for cysteine-rich peptides: a study of conotoxins containing three disulfide bridges
Andrew M. Steiner, Grzegorz Bulaj


Chirality

The use of X-ray crystallography to determine absolute configuration
H. D. Flack, G. Bernardinelli

Assignment of absolute configuration using chiral reagents and NMR spectroscopy
Thomas J. Wenzel, Cora D. Chisholm


Rapid Communication in Mass Spectrometry

Detection, characterization and identification of major constituents in Zhimu-Baihe herb-pair extract by fast high-performance liquid chromatography and time-of-flight mass spectrometry through dynamic adjustment of fragmentor voltage
Keren Wang et al

Effect of mobile phase pH, aqueous-organic ratio, and buffer concentration on electrospray ionization tandem mass spectrometric fragmentation patterns: implications in liquid chromatography/tandem mass spectrometric bioanalysis
Jian Wang et al


The Chemical Record

Nanogel engineering for new nanobiomaterials: from chaperoning engineering to biomedical applications
Yoshihiro Sasaki, Kazunari Akiyoshi


Chinese Journal of Chemistry

Pharmacophore Screening on Piperidinecarboxamides Derivatives Based on GALAHAD and CoMFA Models
Ming Liu, Qiangsan Wu, Wenxiang Hu

Pharmacophore Modeling and in Silico Screening Studies to Design Potential KDR Kinase Inhibitors
Dan Xu, Haopeng Sun, Yadong Chen, Liping Sun, Qidong You

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