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Hottest articles in Biochemistry
Selected from the journals:


Exploring the Substrate Promiscuity of Drug-Modifying Enzymes for the Chemoenzymatic Generation of N-Acylated Aminoglycosides
Keith D. Green, Wenjing Chen, Jacob L. Houghton, Micha Fridman, Sylvie Garneau-Tsodikova

Engineering Allosteric Regulation into Biological Catalysts
Jacques Fastrez

Rationally Engineered Total Biosynthesis of a Synthetic Analogue of a Natural Quinomycin Depsipeptide in Escherichia coli
Kenji Watanabe, Kinya Hotta, Alex P. Praseuth, Mark Searcey, Clay C. C. Wang, Hiroki Oguri,
Hideaki Oikawa

Split Inteins as Versatile Tools for Protein Semisynthesis
Henning D. Mootz

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Angewandte Chemie International Edition
Analysis and Optimization of Copper-Catalyzed Azide-Alkyne Cycloaddition for Bioconjugation
Vu Hong, Stanislav I. Presolski, Celia Ma, M. G. Finn

Spectroscopic Characterization of a Hydroperoxo-Heme Intermediate: Conversion of a Side-On Peroxo to an End-On Hydroperoxo Complex
Jin-Gang Liu, Takehiro Ohta, Satoru Yamaguchi, Takashi Ogura, Satoshi Sakamoto, Yonezo Maeda, Yoshinori Naruta

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Chemistry – A European Journal
Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases
Rajamalleswaramma Jogireddy, Pierre-Yves Dakas, Gaëlle Valot, Sofia Barluenga, Nicolas Winssinger

Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of UV-Induced (6-4) and Dewar Photolesions
Andreas F. Glas, Sabine Schneider, Melanie J. Maul, Ulrich Hennecke, Thomas Carell

Synthetic Mimics of Antimicrobial Peptides - A Versatile Ring-Opening Metathesis Polymerization Based Platform for the Synthesis of Selective Antibacterial and Cell-Penetrating Polymers
Karen Lienkamp, Gregory N. Tew
Molecular Informatics
Support Vector Machine (SVM) as Alternative Tool to Assign Acute Aquatic Toxicity Warning Labels to Chemicals
Lisa Michielan, Luca Pireddu, Matteo Floris, Stefano Moro

Attractors in Sequence Space: Agent-Based Exploration of MHC I Binding Peptides
Natalie Jger, Joanna M. Wisniewska, Jan A. Hiss, Anja Freier, Florian O. Losch, Peter Walden, Paul Wrede, Gisbert Schneider
Chemical Biology & Drug Design
The Structure of Glycosaminoglycans and their Interactions with Proteins
Neha S. Gandhi, Ricardo L. Mancera

Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity
Dirk Beher, John Wu, Suzanne Cumine, Ki Won Kim, Shu-Chen Lu, Larissa Atangan, Minghan Wang

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FEBS Journal
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics
Annette S. Gillings, Kathryn Balmanno, Ceri M. Wiggins, Mark Johnson, Simon J. Cook

Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation
Lindsey A. Allan, Paul R. Clarke
Advanced Functional Materials
Lipid-Like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells
Seung-Woo Cho, Michael Goldberg, Sun Mi Son, Qiaobing Xu, Fan Yang, Ying Mei, Said Bogatyrev, Robert Langer, Daniel G. Anderson

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Cell Biochemistry and Function
Integrating the cell stress response: a new view of molecular chaperones as immunological and physiological homeostatic regulators
Brian Henderson
Chemistry & Biodiversity
Who Is the King? The a-Hydroxy-ß-oxo-a,ß-enone Moiety or the Catechol B Rinf: Relationship between the Structure of Quercetin Derivatives and Their Pro-Oxidative Abilities 
Pei-Yan Liu, Kun Li, Ji Zhang, Da-Wei Zhang, Hong-Hui Lin, and Xiao-Qi Yu

Thermal Wet Decomposition of Prussian Blue: Implications for Prebiotic Chemistry
Marta Ruiz-Bermejo, Celia Rogero, César Menor-Salván, Susana Osuna-Esteban, José Ángel Martín-Gago, Sabino Veintemillas-Verdaguer

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Macromolecular Bioscience
Polymer-Peptide Block Copolymers - An Overview and Assessment of Synthesis Methods
Hana Robson Marsden, Alexander Kros
European Journal of Lipid Science and Technology
Quantification of free and esterified steryl glucosides in vegetable oils and biodiesel
Florence Lacoste, Dr., Franck Dejean, Hugues Griffon, et al

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Helvetica Chimica Acta
Synthesis and High-Resolution NMR Structure of a ß3-Octapeptide with and without a Tether Introduced by Olefin Metathesis
Marc-Olivier Ebert, James Gardiner, Steven Ballet, Andrew D. Abell, Dieter Seebach

ß-Peptide Conjugates: Syntheses and CD and NMR Investigations of ß/a-Chimeric Peptides, of a DPA-ß-Decapeptide, and of a PEGylated ß-Heptapeptide
James Gardiner, Raveendra I. Mathad, Berhard Jaun, Jürg V. Schreiber, Oliver Flögel, Dieter Seebach
Chinese Journal of Chemistry
Colorimetric Sensing of Adenosine Based on Aptamer Binding Inducing Gold Nanoparticle Aggregation
Xueping Liu, Zhenhua Zhou, Liangliang Zhang, Zhongyang Tan, Guoli Shen, Ruqin Yu

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Structured Nucleic Acid Probes for Electrochemical Devices
Rebeca Miranda-Castro, Noemí de-los-Santos-Álvarez, María Jesús Lobo-Castañón, Arturo J. Miranda-Ordieres, Paulino Tuñón-Blanco
Nanogap Field-Effect Transistor Biosensors for Electrical Detection of Avian Influenza
Bonsang Gu, Tae Jung Park, Jae-Hyuk Ahn, Xing-Jiu Huang, Sang Yup Lee, Yang-Kyu Choi

Complementary Electrical and Spectroscopic Detection Assays with On-Wire-Lithography-Based Nanostructures
Gengfeng Zheng, Xiaodong Chen, Chad A. Mirkin

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Journal of Peptide Science
The persisting challenge of selective and specific proteasome inhibition
Michael Groll, Robert Huber, Luis Moroder
Analytical strategies for phosphoproteomics
Tine E. Thingholm, Ole N. Jensen, Martin R. Larsen

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